Jau-Shyong Hong Selected Research

Dextromethorphan (Racemethorphan)

2/2020	Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder.
4/2019	Ultralow doses of dextromethorphan protect mice from endotoxin-induced sepsis-like hepatotoxicity.
10/2015	ALDH2 polymorphism, associated with attenuating negative symptoms in patients with schizophrenia treated with add-on dextromethorphan.
11/2014	Therapeutic effects of add-on low-dose dextromethorphan plus valproic acid in bipolar disorder.
12/2012	Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.
9/2012	Inflammation in patients with schizophrenia: the therapeutic benefits of risperidone plus add-on dextromethorphan.
10/2011	Low dose dextromethorphan attenuates moderate experimental autoimmune encephalomyelitis by inhibiting NOX2 and reducing peripheral immune cells infiltration in the spinal cord.
3/2011	Dextromethorphan efficiently increases bactericidal activity, attenuates inflammatory responses, and prevents group a streptococcal sepsis.
10/2010	Neuropsychopharmacological understanding for therapeutic application of morphinans.
4/2009	Dextromethorphan reduces oxidative stress and inhibits atherosclerosis and neointima formation in mice.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jau-Shyong Hong Research Topics

Disease

48	Inflammation (Inflammations) 09/2021 - 05/2002
43	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2002
29	Neuroinflammatory Diseases 01/2022 - 06/2007
17	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2020 - 04/2005
9	Opioid-Related Disorders (Opiate Addiction) 02/2020 - 02/2006
9	Bipolar Disorder (Manic Depressive Psychosis) 02/2020 - 03/2005
5	Gliosis 11/2021 - 11/2006
4	Sepsis (Septicemia) 02/2020 - 01/2005
4	Mania (Manias) 01/2018 - 11/2014
4	Necrosis 01/2016 - 12/2002
3	Parkinsonian Disorders (Parkinsonism) 01/2021 - 02/2002
3	Mitochondrial Diseases (Mitochondrial Disease) 11/2016 - 08/2011
3	Schizophrenia (Dementia Praecox) 10/2015 - 09/2012
3	Alzheimer Disease (Alzheimer's Disease) 05/2015 - 09/2009
3	Seizures (Absence Seizure) 08/2011 - 12/2002
3	Ischemia 09/2010 - 06/2007
2	Antisocial Personality Disorder (Antisocial Personality) 09/2021 - 11/2017
2	Cognitive Dysfunction 01/2021 - 05/2015
2	Multiple Sclerosis 01/2021 - 10/2011
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2021 - 10/2011
2	Substance-Related Disorders (Drug Abuse) 02/2020 - 11/2017
2	Mood Disorders (Mood Disorder) 02/2020 - 10/2011
2	Endotoxemia 02/2020 - 04/2019
2	Infections 02/2020 - 05/2008
2	Septic Shock (Toxic Shock Syndrome) 04/2019 - 01/2005
2	Alcoholism (Alcohol Abuse) 01/2018 - 02/2006
2	Synucleinopathies 01/2016 - 04/2015
2	Body Weight (Weight, Body) 05/2015 - 03/2004
2	Disease Progression 05/2015 - 04/2005
2	Mental Disorders (Mental Disorder) 06/2014 - 03/2012
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2014 - 06/2007
2	Stroke (Strokes) 01/2014 - 06/2007
2	Cough 10/2011 - 04/2009
2	Nervous System Diseases (Neurological Disorders) 09/2011 - 06/2010
2	Encephalitis (Encephalitis, Rasmussen) 06/2011 - 05/2002
2	Movement Disorders (Movement Disorder) 08/2010 - 03/2004
2	Cicatrix (Scar) 06/2010 - 07/2009
2	Neointima 04/2009 - 11/2006
2	Atherosclerosis 04/2009 - 11/2006

Drug/Important Bio-Agent (IBA)

22	CytokinesIBA 01/2021 - 01/2002
20	Neuroprotective AgentsIBA 01/2021 - 01/2003
17	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022 - 10/2003
16	LipopolysaccharidesIBA 01/2021 - 02/2003
15	Dextromethorphan (Racemethorphan)FDA LinkGeneric 02/2020 - 04/2003
11	Brain-Derived Neurotrophic Factor (BDNF)IBA 09/2021 - 06/2012
11	Superoxides (Superoxide)IBA 01/2021 - 05/2002
10	Memantine (Namenda)FDA Link 01/2021 - 09/2009
9	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2017 - 10/2003
8	Valproic Acid (Depakote)FDA LinkGeneric 02/2020 - 03/2005
7	RotenoneIBA 01/2021 - 02/2002
7	Dopamine (Intropin)FDA LinkGeneric 06/2011 - 02/2004
6	Interleukin-10 (Interleukin 10)IBA 01/2021 - 03/2008
6	Nerve Growth Factors (Neurotrophins)IBA 11/2019 - 09/2009
6	Free RadicalsIBA 08/2014 - 05/2002
6	Naloxone (Narcan)FDA LinkGeneric 02/2012 - 05/2002
5	SynucleinsIBA 01/2021 - 06/2011
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2006
5	Methadone (Dolophine)FDA LinkGeneric 02/2020 - 12/2012
5	Pharmaceutical PreparationsIBA 01/2016 - 04/2005
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2003 - 05/2002
3	Interleukin-8 (Interleukin 8)IBA 01/2021 - 01/2016
3	EnzymesIBA 10/2020 - 05/2015
3	Oxidoreductases (Dehydrogenase)IBA 10/2020 - 01/2011
3	AntioxidantsIBA 10/2020 - 08/2011
3	EndotoxinsIBA 04/2019 - 03/2008
3	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 01/2016 - 01/2004
3	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2016 - 09/2012
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2007 - 01/2002
3	HerbicidesIBA 05/2005 - 02/2002
2	Peptides (Polypeptides)IBA 01/2022 - 01/2016
2	HMGB1 Protein (HMG1)IBA 01/2021 - 01/2011
2	InterleukinsIBA 01/2021 - 01/2016
2	NADP (NADPH)IBA 10/2020 - 05/2015
2	2-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA 11/2019 - 05/2015
2	DSP 4 (DSP-4)IBA 10/2019 - 06/2015
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 10/2019 - 04/2019
2	Transcription Factors (Transcription Factor)IBA 01/2017 - 01/2011
2	IntegrinsIBA 02/2016 - 11/2008
2	Clozapine (Clozaril)FDA LinkGeneric 01/2016 - 03/2012
2	Biomarkers (Surrogate Marker)IBA 01/2016 - 01/2016
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2016 - 01/2016
2	Antipsychotic Agents (Antipsychotics)IBA 01/2016 - 03/2012
2	Fluoxetine (Prozac)FDA LinkGeneric 01/2016 - 01/2012
2	diphenyleneiodoniumIBA 05/2015 - 12/2014
2	Methamphetamine (Desoxyn)FDA LinkGeneric 01/2015 - 06/2012
2	Substance PIBA 09/2014 - 09/2005
2	Opioid Analgesics (Opioids)IBA 12/2012 - 05/2002
2	Dynorphins (Dynorphin)IBA 06/2012 - 09/2005
2	Morphine (MS Contin)FDA LinkGeneric 06/2012 - 09/2005
2	Opioid Receptors (Opioid Receptor)IBA 02/2012 - 09/2002
2	MorphinansIBA 10/2011 - 10/2010
2	Interleukin-6 (Interleukin 6)IBA 04/2009 - 01/2005
2	Apolipoproteins E (ApoE)IBA 04/2009 - 11/2006
2	ApolipoproteinsIBA 04/2009 - 11/2006
2	Histone Deacetylase InhibitorsIBA 12/2008 - 06/2007
2	alpha-SynucleinIBA 08/2007 - 04/2005

Therapy/Procedure

20	Therapeutics 10/2020 - 02/2004
4	Injections 02/2019 - 03/2004
3	Ligation 04/2009 - 09/2005
2	Electrodes (Electrode) 07/2010 - 07/2009